Senile plaques (also known as neuroinflammatory plaques) are extracellular amyloid deposits in the gray matter of the brain.
These deposits may be related to degenerative nerve structure, excessive microglia and astrocytes.
The shape and size of senile plaques are variable. On average, the size of senile plaques is about 50 microns.
The senile plaques in abnormal neurites are mainly composed of paired spiral filaments, which are the components of nerve fiber tangles.
In Alzheimer's disease, these plaques are mainly composed of beta amyloid peptide.
These peptides tend to aggregate automatically, and scientists believe it is neurotoxic.
3 colors / Walnut