A highly soluble microtubule associated protein (map).
TAU PROTEIN
"When tau protein is defective and no longer normally stabilizes microtubules, it can lead to neurological disorders and dementia, such as Alzheimer's disease."
Compared with non neuronal cells, tau is more found in neurons in human body.
One of the main functions of tau protein is to maintain the stability of axon microtubules.
Tau protein interacts with tubulin to stabilize microtubules and drive tubulin assembly in microtubules.
Tau protein controls microtubule stability through isomerization and phosphorylation.
The phosphorylation of tau protein is also congenitally controlled.